Alcohol is an effective fungicide because it is able to penetrate the cell walls and spores of Aspergillus niger, killing it in the process. To use alcohol, apply a liberal amount of a 70% solution to all visible areas of fungus, and let it sit for ten minutes. After 10 minutes of contact time with alcohol, you can wipe the treated area clean and dry it with a clean rag, cloth, or mop. Alcohol is safe for use in the home and in most settings, bearing in mind its highly flammable property. Make sure to avoid using it near any flame or fire source.
Phenols become good fungicidal agents at a concentration of 0. 4% to 0. 5%, because this concentration allows phenols to seep into the core of the fungus’s cell wall and spores, eventually killing it. Phenols can be applied liberally to any surface where you suspect that Aspergillus niger colonies are thriving. Let the phenols sit for about 20 minutes of contact time, then wipe the treated area clean, and dry it with a clean rag, cloth, mop, or another preferred method. However, use phenols with caution if you have infants because it is toxic to them. For adults, phenols are generally safe, but long term exposure can cause skin irritations.
A concentrations of 4-6% of hypochlorite, found in household bleach, not only inhibits the growth of molds, but also kills fungal colonies of Aspergillus niger. A 4-6% hypochlorite solution can be diluted with water in a 1:50 ratio for general surface disinfection and left to dry on the surface. For surfaces that are visibly infected with Aspergillus niger, an undiluted 4-6% solution is ideal to kill the mold. If it is applied in an adequate amount, a contact time of 5-10 minutes can immediately kill Aspergillus niger. After application, the disinfected area can be left to dry or can be wiped clean with a clean rag, cloth, or mop. Note that hypochlorite can cause skin irritations and produces toxic fumes when combined with ammonium compounds or an acid.
This substance is used for high strength disinfection and has great fungicidal effects, as it can destroy the fungus and its spores in a very short period of time. Aldehydes can kill Aspergillus niger with a contact time of around 5 minutes. Wipe down and dry the area treated with aldehyde with a clean rag, cloth, mop or any method you prefer. Unfortunately, long term exposure and contact with this compound is discouraged, because glutaraldehyde is highly carcinogenic.
The usual voriconazole prescription is generally one 200 milligram (mg) each day, for 7 to 14 days. The length of treatment depends on the severity of the infection. [1] X Research source
Amphotericin B is usually available in cream and in ointment form. The cream or ointment is applied topically to any wound or cut infected with A. niger.
It is available in capsule form. The usual prescription is generally 200 to 400 mg, twice a day for seven days. [3] X Research source Trevor, J. , Katzung, G. B. , Masters, B. S. Katzng & Trevor’s Pharmacology 9th edition; McGraw-Hill, 2010
Clotrimazole is generally the go-to topical cream for this infection. It is a 1% otic cream that can be applied to your ear four times a day.
Topical antifungal treatments include Ciclopirox Olamine, an 8% solution, and difenoconazole, a 10% solution.
Treating keratitis caused by this fungus involves topical treatment. Amphotericin B or Natamycin eye drops are generally prescribed for this specific infection. These eye drops are usually administered hourly. [6] X Research source Murray, P. R. , Rosenthal, K. S , Pfaller, M. A. Medical Microbiology 7th Edition; Mosby Elsevier, 1600 John F. Kennedy Blvd. Philadelphia, 2012
Raw garlic contains allicin, a natural compound that has strong antifungal properties and can kill a wide variety of fungus, including Aspergillus niger. Eat 2-3 raw garlic cloves every meal to sufficiently treat Aspergillus niger. You can also take garlic as a non-odorous capsule three times a day. It’s fungicidal effects become apparent when the allicin is absorbed by your stomach and intestines, and then into your bloodstream.
Oleuropein is a strong agent against fungus like Aspergillus niger. Olives are special as an antifungal agent because instead of killing Aspergillus niger immediately, the oleuropein first disrupts the reproductive ability of the fungus. This quickly halts the spread of Aspergillus niger. Then, it cuts off the food supply of the fungus, eradicating Aspergillus niger. Olive oil can be taken orally, by mixing it with your food, or as a topical treatment on skin wounds. A safe and effective intake of olive oil is 25 to 40 mL in a day. [10] X Research source *Fleming, H. (1973). Antimicrobial and Anntifungal Properties of Oleuropein and Products of its Hydrolysis from Green Olives. Applied Microbiology. USA: pp 1496 – 1498
Regular intake of coconut oil also acts as a mild natural laxative that can kill and flush out Aspergillus niger in your digestive system. A recommended antifungal dose of coconut oil is 3 - 6 tablespoons a day or 45 – 90 mL of coconut oil integrated in your food as part of your diet. [12] X Research source *Enig, M. (1996). Health and Nutritional Benefits from Coconut Oil: An Important Functional Food for the 21st Century. Philippines: Manila Printing Press. pp. 119 – 123.
